Prediction of drug-disease associations based on ensemble meta paths and singular value decomposition

Prediction of drug-disease associations based on ensemble meta paths and singular value decomposition

Abstract Background In the field of drug repositioning, it is assumed that similar drugs may treat similar diseases, therefore many existing computational methods need to compute the similarities of drugs and diseases. However, the calculation of similarity depends on the adopted measure and the ava...

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Bibliographic Details
Main Authors: Guangsheng Wu, Juan Liu, Xiang Yue
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Bioinformatics
Subjects:
Drug repositioning
Drug development
Meta path
Commuting matrix
Singular value decomposition
Online Access:http://link.springer.com/article/10.1186/s12859-019-2644-5

Internet

http://link.springer.com/article/10.1186/s12859-019-2644-5

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