Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

Macrophage plasticity enables cells to obtain different functions over a broad proinflammatory and repairing spectrum. In different conditions, macrophages can be induced by high-mobility group box 1 (HMGB1), a nuclear DNA-binding protein that activates innate immunity, to polarize towards a pro- (M...

Full description

Bibliographic Details
Main Authors: Henna Salo, Heshuang Qu, Dimitra Mitsiou, Hannah Aucott, Jinming Han, Xingmei Zhang, Cecilia Aulin, Helena Erlandsson Harris
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomolecules
Subjects:
HMGB1
dsHMGB1
frHMGB1
macrophages
polarization
TLR4
Online Access:https://www.mdpi.com/2218-273X/11/6/800

Internet

https://www.mdpi.com/2218-273X/11/6/800

Similar Items