Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier

Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier

ABSTRACT The blood-brain barrier (BBB) largely prevents toxins and pathogens from accessing the brain. Some viruses have the ability to cross this barrier and replicate in the central nervous system (CNS). Zika virus (ZIKV) was responsible in 2015 to 2016 for a major epidemic in South America and wa...

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Bibliographic Details
Main Authors: Marion Clé, Caroline Desmetz, Jonathan Barthelemy, Marie-France Martin, Orianne Constant, Ghizlane Maarifi, Vincent Foulongne, Karine Bolloré, Yaël Glasson, Frédéric De Bock, Marine Blaquiere, Lucie Dehouck, Nelly Pirot, Edouard Tuaillon, Sébastien Nisole, Fatiha Najioullah, Philippe Van de Perre, André Cabié, Nicola Marchi, Fabien Gosselet, Yannick Simonin, Sara Salinas
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
Zika virus
blood-brain barrier
cell adhesion molecules
leukocyte recruitment
Online Access:https://journals.asm.org/doi/10.1128/mBio.01183-20

Internet

https://journals.asm.org/doi/10.1128/mBio.01183-20

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