Rapid Decrease in Dextrose Concentration After Intra-Articular Knee Injection: Implications for Mechanism of Action of Dextrose Prolotherapy

Background: D-glucose (dextrose) is used as a 5000–25,000 mg% solution in the injection-based pain therapy known as dextrose prolotherapy (DPT). The number of peer-reviewed clinical trials supporting its use is growing. However, the mechanism of action is unknown, limiting further research. A common...

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Bibliographic Details
Main Authors: Kenneth Dean Reeves, Jordan R. Atkins, Clare R. Solso, Chin-I Cheng, Ian M. Thornell, King Hei Stanley Lam, Yung-Tsan Wu, Thomas Motyka, David Rabago
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/13/2/350