SpineTool is an open-source software for analysis of morphology of dendritic spines

Abstract Dendritic spines form most excitatory synaptic inputs in neurons and these spines are altered in many neurodevelopmental and neurodegenerative disorders. Reliable methods to assess and quantify dendritic spines morphology are needed, but most existing methods are subjective and labor intens...

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Bibliographic Details
Main Authors: Ekaterina Pchitskaya, Peter Vasiliev, Daria Smirnova, Vyacheslav Chukanov, Ilya Bezprozvanny
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37406-4