Protoporphyrin IX (PpIX) Fluorescence during Meningioma Surgery: Correlations with Histological Findings and Expression of Heme Pathway Molecules

Background: The usefulness of 5-ALA-mediated fluorescence-guided resection (FGR) in meningiomas is controversial, and information on the molecular background of fluorescence is sparse. Methods: Specimens obtained during 44 FGRs of intracranial meningiomas were analyzed for the presence of tumor tiss...

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Main Authors: Dorothee C. Spille, Eva C. Bunk, Christian Thomas, Zeynep Özdemir, Andrea Wagner, Burak H. Akkurt, Manoj Mannil, Werner Paulus, Oliver M. Grauer, Walter Stummer, Volker Senner, Benjamin Brokinkel
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/1/304