Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

Receptor tyrosine kinases (RTKs) signal through shared intracellular pathways yet mediate distinct outcomes across many cell types. To investigate the mechanisms underlying RTK specificity in craniofacial development, we performed RNA-seq to delineate the transcriptional response to platelet-derived...

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Dettagli Bibliografici
Autori principali: Harish N Vasudevan, Pierre Mazot, Fenglei He, Philippe Soriano
Natura: Articolo
Lingua:English
Pubblicazione: eLife Sciences Publications Ltd 2015-05-01
Serie:eLife
Soggetti:
Accesso online:https://elifesciences.org/articles/07186