Conformational and Immunogenicity Studies of the <i>Shigella flexneri</i> Serogroup 6 O-Antigen: The Effect of O-Acetylation

Conformational and Immunogenicity Studies of the <i>Shigella flexneri</i> Serogroup 6 O-Antigen: The Effect of O-Acetylation

The pathogenic bacterium <i>Shigella</i> is a leading cause of diarrheal disease and mortality, disproportionately affecting young children in low-income countries. The increasing prevalence of antibiotic resistance in <i>Shigella</i> necessitates an effective vaccine, for wh...

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Bibliographic Details
Main Authors: Nicole Inge Richardson, Neil Ravenscroft, Vanessa Arato, Davide Oldrini, Francesca Micoli, Michelle M. Kuttel
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Vaccines
Subjects:
O-antigen
conformation
<i>Shigella flexneri</i>
molecular modeling
GMMA
O-acetylation
Online Access:https://www.mdpi.com/2076-393X/9/5/432

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https://www.mdpi.com/2076-393X/9/5/432

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