Lipoxin A4 promotes autophagy and inhibits overactivation of macrophage inflammasome activity induced by Pg LPS

Lipoxin A4 promotes autophagy and inhibits overactivation of macrophage inflammasome activity induced by Pg LPS

Objective To explore the role of lipoxin A4 (LXA4) on inflammasome and inflammatory activity in macrophages activated by Porphyromonas gingivalis lipopolysaccharide (PgLPS) one of the major causative agents of chronic periodontitis. Methods The mouse macrophage cell line RAW264.7 was used to produce...

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Bibliographic Details
Main Authors: Jie Zhao, Wenjing Geng, Kefei Wan, Kailei Guo, Fengjun Xi, Xiangqun Xu, Xiujuan Xiong, Xu Huang, Jiayi Liu, Xiaodong Kuang
Format: Article
Language:English
Published: SAGE Publishing 2021-02-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520981259

Internet

https://doi.org/10.1177/0300060520981259

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