CD5L induces inflammation and survival in RA-FLS through ERK1/2 MAPK pathway

CD5L induces inflammation and survival in RA-FLS through ERK1/2 MAPK pathway

Objective To explore the effect of CD5-like molecule (CD5L) on rheumatoid arthritis (RA) fibroblast-like synoviocytes (RA-FLS) and the relative molecular mechanism of CD5L in it.Methods Recombinant protein CD5L was used to stimulate the cultured RA-FLS cells. The inflammation-related cytokines were...

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Bibliographic Details
Main Authors: Huiqing Yang, Yan Luo, Xiaofei Lai
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autoimmunity
Subjects:
CD5L
rheumatoid arthritis
inflammatory factors
signalling pathway
proliferation
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2023.2201412

Internet

https://www.tandfonline.com/doi/10.1080/08916934.2023.2201412

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