Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

Sulforaphane (SFN) is a phytochemical compound extracted from cruciferous plants, like broccoli or cauliflower. Its isothiocyanate group renders SFN reactive, thus allowing post-translational modification of cellular proteins to regulate their function with the potential for biological and therapeut...

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Bibliographic Details
Main Authors: Alexandra Rhoden, Felix W. Friedrich, Theresa Brandt, Janice Raabe, Michaela Schweizer, Jana Meisterknecht, Ilka Wittig, Bärbel M. Ulmer, Birgit Klampe, June Uebeler, Angelika Piasecki, Kristina Lorenz, Thomas Eschenhagen, Arne Hansen, Friederike Cuello
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Sulforaphane
Engineered heart tissue
Contractile and mitochondrial function
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000999

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http://www.sciencedirect.com/science/article/pii/S2213231721000999

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