Comparative Analysis of microRNA Binding Site Distribution and microRNA-Mediated Gene Expression Repression of Oncogenes and Tumor Suppressor Genes

MicroRNAs (miRNAs) are a family of short, noncoding RNAs that can regulate gene expression levels of over half of the human genome. Previous studies on the role of miRNAs in cancer showed overall widespread downregulation of miRNAs as a hallmark of human cancer, though individual miRNAs can be both...

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Bibliographic Details
Main Authors: Shuangmei Tian, Jing Wang, Fangyuan Zhang, Degeng Wang
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/3/481