Multi-Antigen Outer Membrane Vesicle Engineering to Develop Polyvalent Vaccines: The Staphylococcus aureus Case

Multi-Antigen Outer Membrane Vesicle Engineering to Develop Polyvalent Vaccines: The Staphylococcus aureus Case

Modification of surface antigens and differential expression of virulence factors are frequent strategies pathogens adopt to escape the host immune system. These escape mechanisms make pathogens a “moving target” for our immune system and represent a challenge for the development of vaccines, which...

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Bibliographic Details
Main Authors: Enrico König, Assunta Gagliardi, Ilary Riedmiller, Chiara Andretta, Michele Tomasi, Carmela Irene, Luca Frattini, Ilaria Zanella, Francesco Berti, Alberto Grandi, Elena Caproni, Laura Fantappiè, Guido Grandi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
Staphylococcus aureus
outer membrane vesicles (OMVs)
chimeric proteins
multivalent vaccines
OMV engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.752168/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.752168/full

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