3-Aminothiophene-2-Acylhydrazones: Non-Toxic, Analgesic and Anti-Inflammatory Lead-Candidates

3-Aminothiophene-2-Acylhydrazones: Non-Toxic, Analgesic and Anti-Inflammatory Lead-Candidates

Different chemotypes are described as anti-inflammatory. Among them the N-acylhydrazones (NAH) are highlighted by their privileged structure nature, being present in several anti-inflammatory drug-candidates. In this paper a series of functionalized 3-aminothiophene-2-acylhydrazone derivatives 5a–...

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Bibliographic Details
Main Authors: Yolanda Karla Cupertino da Silva, Christian Tadeo Moreno Reyes, Gildardo Rivera, Marina Amaral Alves, Eliezer J. Barreiro, Magna Suzana Alexandre Moreira, Lídia Moreira Lima
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Molecules
Subjects:
anti-inflammatory
toxicity
acylhydrazone
analgesic
arthritis
privileged structure
Online Access:http://www.mdpi.com/1420-3049/19/6/8456

Internet

http://www.mdpi.com/1420-3049/19/6/8456

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