Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein

Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein

Lassa mammarenavirus (LASV) is an enveloped RNA virus that can cause Lassa fever, an acute hemorrhagic fever syndrome associated with significant morbidity and high rates of fatality in endemic regions of western Africa. The arenavirus matrix protein Z has several functions during the virus life cyc...

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Bibliographic Details
Main Authors: Christopher M. Ziegler, Philip Eisenhauer, Inessa Manuelyan, Marion E. Weir, Emily A. Bruce, Bryan A. Ballif, Jason Botten
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Pathogens
Subjects:
Lassa virus
Z protein
late domain
PPXY
budding
release
matrix protein
phosphorylation
arenavirus
mass spectrometry
Online Access:https://www.mdpi.com/2076-0817/7/4/97

Internet

https://www.mdpi.com/2076-0817/7/4/97

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