One-Step Affinity Purification of Leucine-Rich α<sub>2</sub>-Glycoproteins from Snake Sera and Characterization of Their Phospholipase A<sub>2</sub>-Inhibitory Activities as β-Type Phospholipase A<sub>2</sub> Inhibitors

One-Step Affinity Purification of Leucine-Rich α<sub>2</sub>-Glycoproteins from Snake Sera and Characterization of Their Phospholipase A<sub>2</sub>-Inhibitory Activities as β-Type Phospholipase A<sub>2</sub> Inhibitors

Snakes contain three types of phospholipase A<sub>2</sub> (PLA<sub>2</sub>)-inhibitory proteins in their blood, PLIα, β, and γ, which protect them from their own venom, PLA<sub>2</sub>. PLIβ is the snake ortholog of leucine-rich α<sub>2</sub> glycoprot...

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Bibliographic Details
Main Authors: Ryoichi Shirai, Kana Shibata, Shinobu Fujii, Rikiro Fukunaga, Seiji Inoue
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Toxins
Subjects:
phospholipase A<sub>2</sub> inhibitor
phospholipase A<sub>2</sub>
leucine-rich α<sub>2</sub>-glycoprotein
cytochrome <i>c</i>
Viperidae
Elapidae
Online Access:https://www.mdpi.com/2072-6651/16/3/126

Internet

https://www.mdpi.com/2072-6651/16/3/126

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