Optimal density of bacterial cells.

A substantial fraction of the bacterial cytosol is occupied by catalysts and their substrates. While a higher volume density of catalysts and substrates might boost biochemical fluxes, the resulting molecular crowding can slow down diffusion, perturb the reactions' Gibbs free energies, and redu...

Full description

Bibliographic Details
Main Authors: Tin Yau Pang, Martin J Lercher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1011177