Topical Drug Delivery of Concentrated Cabazitaxel in an α‐Tocopherol and DMSO Solution

Topical Drug Delivery of Concentrated Cabazitaxel in an α‐Tocopherol and DMSO Solution

Abstract Topical chemotherapy approaches are relevant for certain skin cancer treatments. This study observes that cabazitaxel (CTX), a broad‐spectrum second‐generation taxane cytotoxic agent, can be dissolved in α‐tocopherol at high concentrations exceeding 100 mg mL−1. 2D nuclear magnetic resonanc...

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Bibliographic Details
Main Authors: Boyang Sun, Georgios Paraskevopoulos, Jiwei Min, Robert Rossdeutcher, Sanjana Ghosh, Breandan Quinn, Meng‐Hsuan Lin, Debanjan Sarkar, Dinesh Sukumaran, Yuefei Wang, Kateřina Vávrová, Jonathan F. Lovell, Yumiao Zhang
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Advanced Science
Subjects:
cabazitaxel
skin cancer
transdermal delivery
α‐tocopherol
Online Access:https://doi.org/10.1002/advs.202302658

Internet

https://doi.org/10.1002/advs.202302658

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