Methadone interrupts neural growth and function in human cortical organoids
Prenatal opioids exposure can lead to both neonatal abstinence syndrome in newborns and neurological deficits later in life. Although opioids have been well studied in general, the cellular and molecular mechanisms by which opioids affect human fetal brain development has not been well understood. I...
Main Authors: | Hang Yao, Wei Wu, Ines Cerf, Helen W. Zhao, Juan Wang, Priscilla D. Negraes, Alysson R. Muotri, Gabriel G. Haddad |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | Stem Cell Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506120303664 |
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