Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter

Abstract Epidemiological studies have demonstrated that the use of antidepressants is associated with a decreased risk of colorectal cancer (CRC); however, the mechanisms behind this association are yet unknown. Adrenergic system contributes to the stress-related tumor progression, with norepinephri...

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Bibliographic Details
Main Authors: Huahua Zhang, Jiming Han, Jing Zhang, Jiyu Miao, Fang Li, Kaijie Tang, Kai Zhou, Baojun Duan, Wen Li, Jing Cheng, Ying Sun, Ni Hou, Chen Huang
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01447-5