<i>N</i>-Heterocyclic Carbene-Iridium Complexes as Photosensitizers for In Vitro Photodynamic Therapy to Trigger Non-Apoptotic Cell Death in Cancer Cells

<i>N</i>-Heterocyclic Carbene-Iridium Complexes as Photosensitizers for In Vitro Photodynamic Therapy to Trigger Non-Apoptotic Cell Death in Cancer Cells

A series of seven novel iridium complexes were synthetized and characterized as potential photosensitizers for photodynamic therapy (PDT) applications. Among them, four complexes were evaluated in vitro for their anti-proliferative activity with and without irradiation on a panel of five cancer cell...

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Bibliographic Details
Main Authors: Xing Wang, Chen Zhang, Ryma Madji, Camille Voros, Serge Mazères, Christian Bijani, Céline Deraeve, Olivier Cuvillier, Heinz Gornitzka, Marie-Lise Maddelein, Catherine Hemmert
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
iridium
<i>N</i>-heterocyclic carbene
luminescence
photodynamic therapy
cell death
apoptosis
Online Access:https://www.mdpi.com/1420-3049/28/2/691

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https://www.mdpi.com/1420-3049/28/2/691

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