Regionally enriched rare deleterious exonic variants in the UK and Ireland

Regionally enriched rare deleterious exonic variants in the UK and Ireland

Abstract It is unclear how patterns of regional genetic differentiation in the UK and Ireland might impact the protein-coding fraction of the genome. We exploit UK Biobank (UKB) and Viking Genes whole exome sequencing data to study regional genetic differentiation across the UK and Ireland in protei...

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Bibliographic Details
Main Authors: Mihail Halachev, Viktoria-Eleni Gountouna, Alison Meynert, Gannie Tzoneva, Alan R. Shuldiner, Colin A. Semple, James F. Wilson
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51604-2

Internet

https://doi.org/10.1038/s41467-024-51604-2

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