Double DAP-seq uncovered synergistic DNA binding of interacting bZIP transcription factors

Double DAP-seq uncovered synergistic DNA binding of interacting bZIP transcription factors

Abstract Many eukaryotic transcription factors (TF) form homodimer or heterodimer complexes to regulate gene expression. Dimerization of BASIC LEUCINE ZIPPER (bZIP) TFs are critical for their functions, but the molecular mechanism underlying the DNA binding and functional specificity of homo- versus...

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Bibliographic Details
Main Authors: Miaomiao Li, Tao Yao, Wanru Lin, Will E. Hinckley, Mary Galli, Wellington Muchero, Andrea Gallavotti, Jin-Gui Chen, Shao-shan Carol Huang
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38096-2

Internet

https://doi.org/10.1038/s41467-023-38096-2

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