Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth

Abstract Background A recent study has shown that it is possible to accurately estimate gestational age (GA) at birth from the DNA methylation (DNAm) of fetal umbilical cord blood/newborn blood spots. This DNAm GA predictor may provide additional information relevant to developmental stage. In 814 m...

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Bibliographic Details
Main Authors: Polina Girchenko, Jari Lahti, Darina Czamara, Anna K. Knight, Meaghan J. Jones, Anna Suarez, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Pia M. Villa, Rebecca M. Reynolds, Michael S. Kobor, Alicia K. Smith, Elisabeth B. Binder, Katri Räikkönen
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Clinical Epigenetics
Subjects:
Aging
Cord blood methylation
Epigenetic clock
Gestational age
Prenatal programming
Online Access:http://link.springer.com/article/10.1186/s13148-017-0349-z

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http://link.springer.com/article/10.1186/s13148-017-0349-z

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