Modelling premature cardiac aging with induced pluripotent stem cells from a hutchinson-gilford Progeria Syndrome patient

Modelling premature cardiac aging with induced pluripotent stem cells from a hutchinson-gilford Progeria Syndrome patient

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes accelerated aging and a high risk of cardiovascular complications. However, the underlying mechanisms of cardiac complications of this syndrome are not fully understood. This study modeled HGPS using cardiomyocytes (C...

Full description

Bibliographic Details
Main Authors: Gustavo Monnerat, Tais Hanae Kasai-Brunswick, Karina Dutra Asensi, Danubia Silva dos Santos, Raiana Andrade Quintanilha Barbosa, Fernanda Cristina Paccola Mesquita, Joao Paulo Calvancanti Albuquerque, Pires Ferreira Raphaela, Camila Wendt, Kildare Miranda, Gilberto Barbosa Domont, Fábio César Sousa Nogueira, Adriana Bastos Carvalho, Antonio Carlos Campos de Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Physiology
Subjects:
aging
progeria
proteomics
pluripotent stem cell (PSC)
cardiology
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1007418/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.1007418/full

Similar Items