Characterization of Conformational Ensembles of Protonated N-glycans in the Gas-Phase

Abstract Ion mobility mass spectrometry (IM-MS) is a technique capable of investigating structural changes of biomolecules based on their collision cross section (CCS). Recent advances in IM-MS allow us to separate carbohydrate isomers with subtle conformational differences, but the relationship bet...

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Bibliographic Details
Main Authors: Suyong Re, Shigehisa Watabe, Wataru Nishima, Eiro Muneyuki, Yoshiki Yamaguchi, Alexander D. MacKerell, Yuji Sugita
Format: Article
Language:English
Published: Nature Portfolio 2018-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-20012-0