Genetic variation in the <it>Catechol-O-Methyltransferase (COMT) </it>gene and morphine requirements in cancer patients with pain
<p>Abstract</p> <p>Background</p> <p>Genetic variation contributes to differences in pain sensitivity and response to different analgesics. Catecholamines are involved in the modulation of pain and are partly metabolized by the catechol-O-methyltransferase (COMT) enzyme...
Main Authors: | Kaasa Stein, Skorpen Frank, Sato Hiroe, Ross Joy R, Rakvåg Trude T, Klepstad Pål |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2008-12-01
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Series: | Molecular Pain |
Online Access: | http://stephenslab.uchicago.edu/home.html |
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