Efficient and crucial quality control of HAP1 cell ploidy status

Efficient and crucial quality control of HAP1 cell ploidy status

The near-haploid human cell line HAP1 recently became a popular subject for CRISPR/Cas9 editing, since only one allele requires modification. Through the gene-editing service at Horizon Discovery, there are at present more than 7500 edited cell lines available and the number continuously increases....

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Bibliographic Details
Main Authors: Tobias B. Beigl, Ine Kjosås, Emilie Seljeseth, Nina Glomnes, Henriette Aksnes
Format: Article
Language:English
Published: The Company of Biologists 2020-11-01
Series:Biology Open
Subjects:
hap1
near-haploid human cell line
crispr/cas9
gene editing
clustered palindromic repeats
cas9 enzyme
cell phenotype analyses
microscopy genetic disease cell model
cell culture quality control
Online Access:http://bio.biologists.org/content/9/11/bio057174

Internet

http://bio.biologists.org/content/9/11/bio057174

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