Genetic liability to rheumatoid arthritis on autism and autistic traits: polygenic risk score and Mendelian randomization analyses

Abstract Higher prevalence of autism in offspring born to mothers with rheumatoid arthritis has been reported in observational studies. We investigated (a) the associations between maternal and offspring’s own genetic liability for rheumatoid arthritis and autism-related outcomes in the offspring us...

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Bibliographic Details
Main Authors: Amanda Ly, Beate Leppert, Dheeraj Rai, Hannah Jones, Christina Dardani, Evie Stergiakouli
Format: Article
Language:English
Published: Nature Publishing Group 2022-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01772-2