Viral-induced alternative splicing of host genes promotes influenza replication

Viral-induced alternative splicing of host genes promotes influenza replication

Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that infection of human lung epithelial cells with influenza A virus (IAV) also induces a broad program of alternative splicing of host genes. Although these splicing-regulated genes are...

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Bibliographic Details
Main Authors: Matthew G Thompson, Mark Dittmar, Michael J Mallory, Prasanna Bhat, Max B Ferretti, Beatriz MA Fontoura, Sara Cherry, Kristen W Lynch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
virus infection
alternative splicing
hnRNP K
influenza
Online Access:https://elifesciences.org/articles/55500

Internet

https://elifesciences.org/articles/55500

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