A Microbiota-Dependent Subset of Skin Macrophages Protects Against Cutaneous Bacterial Infection

Microbiota is essential to the development and functional maturation of the immune system. The effects of the gut microbiota on myeloid cells remote from the gut, especially the skin remain unclear. Transcriptomic analysis revealed that type I interferon (IFN) signaling was down-regulated in the ski...

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Bibliographic Details
Main Authors: Young Joon Park, Byeong Hoon Kang, Hyun-Jin Kim, Ji Eun Oh, Heung Kyu Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.799598/full