Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Background: The pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and mechanisms underlying different responses to systemic glucocorticoids (GC) remain unclear. The major aim of this study was to explore the transcriptomic and oxidative lipidomic signatures and the effects of GC in p...

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Bibliographische Detailangaben
Hauptverfasser: Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Lei Wang, Jinbo Han, Jianmin Zhang, Wei Lv
Format: Artikel
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2022-01-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
Online Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2021.814953/full