Single-domain antibody-based protein degrader for synucleinopathies
Abstract Synucleinopathies are a group of neurodegenerative diseases characterized by the accumulation of α-synuclein (α-syn) in the brain, leading to motor and neuropsychiatric symptoms. Currently, there are no known cures for synucleinopathies, and treatments mainly focus on symptom management. In...
Huvudupphovsmän: | , , , , , , , |
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Materialtyp: | Artikel |
Språk: | English |
Publicerad: |
BMC
2024-05-01
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Serie: | Molecular Neurodegeneration |
Länkar: | https://doi.org/10.1186/s13024-024-00730-y |