Neuroprotective effect of Ziziphi Spinosae Semen on rats with p-chlorophenylalanine-induced insomnia via activation of GABAA receptor

Neuroprotective effect of Ziziphi Spinosae Semen on rats with p-chlorophenylalanine-induced insomnia via activation of GABAA receptor

Ziziphus jujuba var. spinosa (Bunge) Hu ex H.F.Chow [Rhamnaceae; Ziziphi Spinosae Semen (ZSS)] has attracted extensive attention as the first choice of traditional Chinese medicine in the treatment of insomnia. However, recent studies on the sleep-improving mechanism of ZSS have mainly focused on th...

Full description

Bibliographic Details
Main Authors: Fengqin Xiao, Shuai Shao, Hongyin Zhang, Guangfu Li, Songlan Piao, Daqing Zhao, Guangzhe Li, Mingming Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
Ziziphi Spinosae Semen
insomnia
para-chlorophenylalanine
GABAARα1
GABAARγ2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.965308/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.965308/full

Similar Items