Proteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinoma

Proteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinoma

ABSTRACT: The clinical management of locally advanced oesophageal adenocarcinoma (OAC) involves neoadjuvant chemoradiotherapy (CRT), but as radioresistance remains a major clinical challenge, complete pathological response to CRT only occurs in 20–30% of patients. In this study we used an establishe...

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Bibliographic Details
Main Authors: Simone Marcone, Amy Buckley, Colm J. Ryan, Mark McCabe, Niamh Lynam-Lennon, David Matallanas, Jacintha O`Sullivan, Susan Kennedy
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cancer Treatment and Research Communications
Subjects:
Radioresistance
Proteomics
Cancer metabolism
Inflammation
Angiogenesis
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2468294221000745

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http://www.sciencedirect.com/science/article/pii/S2468294221000745

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