Influence of traditional Chinese medicines on the in vivo metabolism of lopinavir/ritonavir based on UHPLC-MS/MS analysis

Influence of traditional Chinese medicines on the in vivo metabolism of lopinavir/ritonavir based on UHPLC-MS/MS analysis

A fast, reliable, and cost-effective liquid chromatography-tandem mass spectrometry method was established to determine the effects of the traditional Chinese medicine employed to treat coronavirus disease 2019, namely, Lianhua Qingwen granules, Huoxiang Zhengqi capsules, Jinhua Qinggan granules, Sh...

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Bibliographic Details
Main Authors: Linlin Li, Xinxiang Yu, Dongmin Xie, Ningning Peng, Weilin Wang, Decai Wang, Binglong Li
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Lopinavir/ritonavir
Combination of Chinese and western medicine
Drug-drug interaction
Ultra high-performance liquid chromatography-tandem mass spectrometry
Pharmacokinetics
COVID-19
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177921000666

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http://www.sciencedirect.com/science/article/pii/S2095177921000666

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