Synthesis and Characterization of Store-Operated Calcium Entry Inhibitors Active in the Submicromolar Range

The store-operated calcium entry, better known as SOCE, forms the main Ca<sup>2+</sup> influx pathway in non-excitable cells, especially in leukocytes, where it is required for cell activation and the immune response. During the past decades, several inhibitors were developed, but they l...

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Bibliographic Details
Main Authors: Camille Le Guilcher, Tomas Luyten, Jan B. Parys, Mathieu Pucheault, Olivier Dellis
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/24/9777