Regulation of chromatin accessibility and gene expression in the developing hippocampal primordium by LIM-HD transcription factor LHX2.

In the mammalian cerebral cortex, the hippocampal primordium (Hcp) occupies a discrete position in the dorsal telencephalic neuroepithelium adjacent to the neocortical primordium (Ncp). We examined transcriptomic and chromatin-level features that distinguish the Hcp from the Ncp in the mouse during...

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Main Authors: Varun Suresh, Bhavana Muralidharan, Saurabh J Pradhan, Mahima Bose, Leora D'Souza, Arpan Parichha, Puli Chandramouli Reddy, Sanjeev Galande, Shubha Tole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010874&type=printable