MiR-103a-3p Promotes Zika Virus Replication by Targeting OTU Deubiquitinase 4 to Activate p38 Mitogen-Activated Protein Kinase Signaling Pathway

MiR-103a-3p Promotes Zika Virus Replication by Targeting OTU Deubiquitinase 4 to Activate p38 Mitogen-Activated Protein Kinase Signaling Pathway

BackgroundMicroRNAs (miRNAs) play critical roles in regulating virus infection and replication. However, the mechanism by which miRNA regulates Zika virus (ZIKV) replication remains elusive. We aim to explore how the differentially expressed miR-103a-3p regulates ZIKV replication and to clarify the...

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Bibliographic Details
Main Authors: Haiyan Ye, Lan Kang, Xipeng Yan, Shilin Li, Yike Huang, Rongrong Mu, Xiaoqiong Duan, Limin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Microbiology
Subjects:
MiR-103a-3p
Zika virus
flavivirus
OTUD4
p38 MAPK signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.862580/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.862580/full

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