Transcriptomic characterization of dying hair cells in the avian cochlea

Summary: Sensory hair cells are prone to apoptosis caused by various drugs including aminoglycoside antibiotics. In mammals, this vulnerability results in permanent hearing loss because lost hair cells are not regenerated. Conversely, hair cells regenerate in birds, making the avian inner ear an exq...

Full description

Bibliographic Details
Main Authors: Nesrine Benkafadar, Amanda Janesick, Mirko Scheibinger, Angela H. Ling, Taha A. Jan, Stefan Heller
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721002163