Sinococuline, a bioactive compound of Cocculus hirsutus has potent anti-dengue activity

Abstract Dengue virus (DENV) infection has increased worldwide, with over 400 million infections annually, and has become a serious public health concern. Several drug candidates, new and repurposed, have failed to meet the primary efficacy endpoints. We have recently shown that Aqueous Extract of t...

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Bibliographic Details
Main Authors: Rahul Shukla, Richa Ahuja, Hemalatha Beesetti, Amit Garg, Charu Aggarwal, Shivam Chaturvedi, Kaushal Nayyar, Upasana Arora, Altaf A. Lal, Navin Khanna
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-27927-3