High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2 Mycobacterium tuberculosis clones in the Mumbai Metropolitan Region

High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2 Mycobacterium tuberculosis clones in the Mumbai Metropolitan Region

Abstract Background Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains are a serious health problem in India, also contributing to one-fourth of the global MDR tuberculosis (TB) burden. About 36% of the MDR MTBC strains are reported fluoroquinolone (FQ) resistant leading to...

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Bibliographic Details
Main Authors: Viola Dreyer, Ayan Mandal, Prachi Dev, Matthias Merker, Ivan Barilar, Christian Utpatel, Kayzad Nilgiriwala, Camilla Rodrigues, Derrick W. Crook, the CRyPTIC Consortium, Jean-Philippe Rasigade, Thierry Wirth, Nerges Mistry, Stefan Niemann
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Genome Medicine
Subjects:
Tuberculosis
Resistant TB
Multidrug-resistant TB
Fluoroquinolone resistance
India; Pre-XDR/XDR-TB
Pre-XDR/XDR-TB transmission
Online Access:https://doi.org/10.1186/s13073-022-01076-0

Internet

https://doi.org/10.1186/s13073-022-01076-0

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