Disruption of Col9a2 expression leads to defects in osteochondral homeostasis and osteoarthritis-like phenotype in mice

Background/Objective: As one of the branched chains of Type IX collagen (Col9), Collagen IX alpha2 (Col9a2) has been reported to be associated with several orthopedic conditions. However, the relationship between Col9a2 and knee osteoarthritis (KOA) remains to be elucidated. Methods: To probe the re...

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Bibliographic Details
Main Authors: Rui Dong, Huihui Xu, Pinger Wang, Liang Fang, Luwei Xiao, Shuaijie Lv, Peijian Tong, Hongting Jin
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X23000591