Cytometry profiling of ex vivo recall responses to Coxiella burnetii in previously naturally exposed individuals reveals long-term changes in both adaptive and innate immune cellular compartments

IntroductionQ fever, caused by the intracellular bacterium Coxiella burnetii, is considered an occupational and biodefense hazard and can result in debilitating long-term complications. While natural infection and vaccination induce humoral and cellular immune responses, the exact nature of cellular...

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Bibliographic Details
Main Authors: Susan Raju Paul, Anja Scholzen, Patrick M. Reeves, Robert Shepard, Joshua M. Hess, Richard K. Dzeng, Skylar Korek, Anja Garritsen, Mark C. Poznansky, Ann E. Sluder
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1249581/full