The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
<p>The heterotrimeric G-protein alpha subunit has long been considered a bimodal, GTP-hydrolyzing switch controlling the duration of signal transduction by seven-transmembrane domain (7TM) cell-surface receptors. In 1996, we and others identified a superfamily of “regulator of G-prot...
Format: | Article |
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Language: | English |
Published: |
Ivyspring International Publisher
2005-04-01
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Series: | International Journal of Biological Sciences |
Subjects: | |
Online Access: | http://www.biolsci.org/v01p0051.htm |