The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

<p>The heterotrimeric G-protein alpha subunit has long been considered a bimodal, GTP-hydrolyzing switch controlling the duration of signal transduction by seven-transmembrane domain (7TM) cell-surface receptors. In 1996, we and others identified a superfamily of &#8220;regulator of G-prot...

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Bibliographic Details
Format: Article
Language:English
Published: Ivyspring International Publisher 2005-04-01
Series:International Journal of Biological Sciences
Subjects:
Online Access:http://www.biolsci.org/v01p0051.htm