An integrated bioinformatic investigation of mitochondrial energy metabolism genes in colon adenocarcinoma followed by preliminary validation of CPT2 in tumor immune infiltration

An integrated bioinformatic investigation of mitochondrial energy metabolism genes in colon adenocarcinoma followed by preliminary validation of CPT2 in tumor immune infiltration

BackgroundThe prognosis for colon adenocarcinoma (COAD) today remains poor. Changes in mitochondria-related genes and metabolic reprogramming are related to tumor growth, metastasis, and immune evasion and are key factors in tumor genesis and development.MethodsTCGA database was used to analyze the...

Full description

Bibliographic Details
Main Authors: Zichao Cao, Jianwei Lin, Gang Fu, Lingshan Niu, Zheyu Yang, Wei Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
mitochondrion
energy metabolism
colon adenocarcinoma
immune
CPT2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.959967/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.959967/full

Similar Items