A Series of Barbituric Acid Derivatives from Sulfa Drug: Synthesis and Antimicrobial Activity
This paper reports the synthesis and characterization of some new barbituric acid derivatives from sulfadiazine. A reaction of sulfadiazine with chloroacetyl chloride gave 2-chloro-N-(4-(N-pyrimidin-2-ylsulfamoyl) phenyl) acetamide [A] which was reacted with thiourea and K2CO3 to give thiazole deriv...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2019-03-01
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| Series: | Nano Biomedicine and Engineering |
| Subjects: | |
| Online Access: | https://www.sciopen.com/article/10.5101/nbe.v11i1.p67-83 |