Lymphocyte apoptosis and its association with the inflammatory markers and disease severity in juvenile-onset systemic lupus erythematosus patients

Lymphocyte apoptosis and its association with the inflammatory markers and disease severity in juvenile-onset systemic lupus erythematosus patients

Abstract Background The defective clearance of apoptotic bodies in juvenile-onset systemic lupus erythematosus (jSLE) potentially leads to the persistence of autoreactive lymphocytes and the perpetuation of the autoimmune response. These factors contribute to the disturbance in lymphocyte apoptosis...

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Bibliographic Details
Main Authors: Eman Eissa, Rania Kandil, Dalia Dorgham, Raghda Ghorab, Naglaa Kholoussi
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Juvenile-onset systemic lupus erythematosus
Lymphocyte apoptosis
Flow cytometry
Inflammatory cytokines
IL-17
IFN-γ
Online Access:https://doi.org/10.1186/s12969-024-00953-9

Internet

https://doi.org/10.1186/s12969-024-00953-9

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