Are Mouse Models of Asthma Appropriate for Investigating the Pathogenesis of Airway Hyper-Responsiveness?
Whether mouse models of chronic asthma can be used to investigate the relationship between airway inflammation/remodelling and airway hyper-responsiveness (AHR) is a vexed question. It raises issues about the extent to which such models replicate key features of the human disease. Here, we review so...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-07-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00312/full |