Schlafen-5 inhibits LINE-1 retrotransposition

Schlafen-5 inhibits LINE-1 retrotransposition

Summary: Long interspersed element 1 (LINE-1) is the only currently known active autonomous transposon in humans, and its retrotransposition may cause deleterious effects on the structure and function of host cell genomes and result in sporadic genetic diseases. Host cells therefore developed defens...

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Bibliographic Details
Main Authors: Jiwei Ding, Shujie Wang, Qipeng Liu, Yuqing Duan, Tingting Cheng, Zhongjie Ye, Zhanding Cui, Ao Zhang, Qiuyu Liu, Zixiong Zhang, Ning Zhang, Qian Liu, Ni An, Jianyuan Zhao, Dongrong Yi, Quanjie Li, Jing Wang, Yongxin Zhang, Ling Ma, Saisai Guo, Jinhui Wang, Chen Liang, Jinming Zhou, Shan Cen, Xiaoyu Li
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Molecular biology
Molecular genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422302045X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422302045X

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